The Secret Miracles of Noni Enzyme

The Iridoid Difference

Phytochemicals ( Noni Benefit )

The history of published medical research on noni phytochemicals numbers only around a total of 110 reports, which began appearing in the 1950s (searched in September 2008). Just since 2000, over 100 publications on noni have been published in medical literature, defining a relatively young research field. Noni benefits research is at a preliminary stage, as it is mainly still in the laboratory as in vitro or basic animal experiments.

Noni fruit contains noni benefits phytochemicals for which there are no established DRI values. Examples:

  * lignans - a group of phytoestrogens having biological activities shown by in vitro experiments
  * oligo- and polysaccharides - long-chain sugar molecules that serve a prebiotic function as dietary fiber fermentable by colonic bacteria, yielding short chain fatty acids with numerous potential health properties not yet defined by scientific research on noni
  * flavonoids - phenolic compounds such as rutin and asperulosidic acid, common in several Rubiaceae plants
  * iridoids - secondary metabolites found in many plants
  * trisaccharide fatty acid esters, "noniosides" - resulting from combination of an alcohol and an acid in noni fruit
  * free fatty acids - most prominent in noni fruit are caprylic acid and hexanoic acid, responsible for unique pungent (cheese-like) aroma of ripe noni fruit
  * scopoletin - may have antibiotic activities; research is preliminary
  * catechin and epicatechin
  * beta-sitosterol - a plant sterol with potential for anti-cholesterol activity not yet proven in human research
  * damnacanthal - a potentially toxic anthraquinone, putatively an inhibitor of HIV viral proteins
  * alkaloids - naturally occurring amines from plants. Some internet references mention xeronine or proxeronine as important noni constituents. However, as no reports on either of these substances exist in published medical literature, the terms are scientifically unrecognized. Further, chemical analysis of commercially processed juice did not reveal presence of any alkaloids.

Although there is evidence from in vitro studies and laboratory models for bioactivity of each of the above phytochemicals, the research remains at best preliminary and too early to conclude anything about human health benefits provided by noni or its juice. Furthermore, these phytochemicals are not unique to noni, as nearly all exist in various plant foods.

Laboratory experiments demonstrated that dietary noni juice increased physical endurance in mice. A pilot study in distance runners showed increased endurance capacity following daily intake of noni juice over three weeks, an effect the authors attributed to increased antioxidant status. more

FLAVONOID CONTENT OF MORINDA CITRIFOLIA

Antioxidant Activity and Content Of Morinda Citrifolia Fruit Extracts 71
1. Introduction
Plants such as herbs have been used in folk medicine for centuries in most of the cultures throughout the world. Morinda citrifolia L. native to Polynesia is one of the traditional folk medicinal plants that have been used for over 2000 years by polynesians for treating diabetes, high blood pressure, cancer, eye problems and many other illnesses [1].
Generation of free radicals or reactive oxygen species (ROS) during metabolism and other activities beyond the antioxidant capacity of a biological system gives rise to oxidative stress [2]. Oxidative stress plays a role in heart diseases, neurodegenerative diseases, cancer and in the aging process [3]. This concept is supported by increasing evidence that oxidative damage plays a role in the development of chronic, age-related degenerative diseases, and that dietary antioxidants oppose this and lower risk of disease [4]. Antioxidants are the substance that when present in low concentrations compared to those of an oxidisable substrate significantly delays or prevents oxidation of that substance [5].
Apart from their role of health benefactors, antioxidants are added in foods to prevent or delay oxidation of food, initiated by free radicals formed during their exposure to environmental factors such as air, light and temperature [6]. At present most of the antioxidants are manufactured synthetically. They belong to the class of synthetic antioxidants. The main disadvantage with the synthetic antioxidants is the side effects when taken in vivo [7]. Strict governmental rules regarding the safety of the food has necessitated the search for alternatives as food preservatives [8]. more

Extract Dari Daun Mengkudu

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

The present invention comprises various methods of producing leaf extracts from the leaves of the Indian Mulberry or Morinda citrifolia L. plant. In addition, the present invention comprises various methods for creating a leaf serum by combining the leaf extracts with fruit juice of the Morinda citrifolia plant. Methods of the present invention also include incorporating the leaf serum into a pharmaceutical leaf product (“pharmaceutical” herein referring to any drug or product designed to improve the health of living organisms such as a human beings or mammals, including nutraceutical products). Still further, the present invention comprises various leaf extract compositions, including leaf extracts, leaf serum, and pharmaceutical products having leaf serum incorporated therein. Further details of the present invention are described below.

In some embodiments of the present invention, the Morinda citrifolia leaf extracts are obtained using a highly technical and precise process. First, relatively dry leaves from the Morinda citrifolia L. plant are collected, cut into small pieces, and placed into a crushing device, preferably a hydraulic press, where the leaf pieces are crushed. The crushed leaf pieces are then percolated with an alcohol such as ethanol, methanol, ethyl acetate, or other alcohol-based derivatives using methods known in the art. Next, the alcohol and all alcohol-soluble ingredients are extracted from the crushed leaf pieces, leaving a leaf extract that is then reduced with heat to remove all the liquid therefrom. The resulting dry leaf extract will herein be referred to as the “primary leaf extract.”

In some embodiments of the present invention, the primary leaf extract is pasteurized to at least partially sterilize the extract and destroy objectionable organisms. The primary leaf extract is pasteurized preferably at a temperature ranging from 70 to 80 degrees Celsius and for a period of time sufficient to destroy any objectionable organisms without major chemical alteration of the extract. Pasteurization may also be accomplished according to various radiation techniques or methods. see more

Noni Science

Clinical Practice And Studies
The National Institute of Health has funded studies of Noni Juice (morinda citrifolia) since the 1950's at the Univerity of Hawaii. The Cancer Research Center in Hawaii is currently in Phase II of it's clinical trials using Noni as a cancer treatment. Noni is still used by the local population in Hawaii for sugar control diseases, high vascular pressure, heart health maintenance, abnormal growths, and other chronic disorders, although no controlled clinical studies exist to support these uses. Based on clinical practice and animal studies, a polysaccharide-rich substance from noni fruit juice attacks abnormal cells in several different ways.   see more

Polynesian Noni Juice - 32oz bottle

Noni (morinda citrifolia) is quite possibly one of the world's best natural adaptogens, it has been used for hundreds of years by the native Polynesians as a natural food supplement and health tonic. People of Polynesia were, and still are great believers in the fruit as a natural remedy and exported plants everywhere in the Pacific region, including Hawaii. An interesting study of the early use of the fruit in Hawaii indicates that Noni may have been the only good source of vitamin C in the islands in ancient times and it was said to have helped the islanders survive. The natives used all parts of the noni plant, the fruit, the seeds, the leaves as well as the flowers as a medicine, as a food or for topical skin care.

There are currently dozens of producers of Noni Juice on the market. Some Noni Juice drinks are reconstituted from noni powders; others are made from Noni fruit pulp diluted with water. Very few Noni drinks sold contain at least 85% pure Noni juice, but according to clever marketing efforts, they appear to be 100% pure, until you read the fine print on the ingredient label. Many sellers look for ways to dilute Noni so as to maximize profits. Why purchase reconstituted and flavored noni juice when you can purchase unadulterated Noni Juice for less than half the price of what other companies sell it for? see the site

Mengkudu

Mengkudu nama saintifiknya Morinda Citrifolia berasal dari Asia Tenggara, Australia, kepulauan  Pasifik.  Saya masih ingat semasa kecil arwah mak dan nenek selaian mengguna mengkudu sebagai ubat, mereka juga membersih barang barang emas mengguna mengkudu.  Mak masukan cincin, rantai dan gelang emas dalam buah mengkudu yang masak dan simpan semalam, esok pagi mak akan bilas dengan air bersih dan sapu hingga kering. Emas yang berkilat dan memancar itu boleh tahan beberapa bulan dan nampak seperti baru.
Kajian klinik menunjukkan manfaat mengkudu antara lain:

• Menurunkan tekanan darah tinggi
• Bersama Melatonin dan Serotonin memperbaiki kualiti tidur dan peredaran darah.
• Memberikan tenaga pada tubuh.
• Bertindak sebagai anti radang (penahan sakit) dan anti Histimik.
• Anti bakteria, khususnya melindungi kerusakan sistem pencernaan dan jantung.
• Menghentikan fungsi pra kanser dan pertumbuhan kanser.
• Memperbaiki sistem imuniti (rangsangan untuk menghasilkan sel T)
• Memperlambat proses penuaan sel (awet muda)
• Mencegah Diabetes tahap 1 & 2, stress, ginjal dan strok.

Banyak kajian turut dijalankan di Amerika Syarikat di Stanford University, Unifersity of California, UCLA, University College of London, University of Meet, France. Kesemuanya bersetuju peranan menkudu dalam merendahkan darah tinggi.
Kajian Dr.Scott Gerson, M.D. menunjukkan penurunan purata 7.5% (sistolik) dan 4% (diastolic) bagi pesakit lelaki.  Dr. Monica Harrison dari Maryland juga melaporkan penurunan bagi ujian terhadap wanita dengan tekanan darahnya 170/100 kepada 130/80 selepas mengambil mengkudu.  Dr. Harrison percaya mengkudu mampu meningkatkan aktiviti ‘pineal gland’ yang terletak di bahagian dalam otak.  Serotonin yang terdapat dalam mengkudu digunakan oleh kelenjar ini untuk menghasilkan hormone melatonin.
Makmal pharmacosny, University of Meets, Perancis telah menjumpai mengkudu mempunyai kesan ‘central analgesic’ iaitu memberi kesan ke atas otak bagi melegakan kesakitan di seluruh tubuh.  Kajian menunjukkan keberkesanan 75% dari morphine sebagai melegakan kesakitan, cuma mengkudu tidak meninggalkan kesan ketagihan dan toksik.
* HASIL PENELITIAN 40 AHLI PENGUBATAN TERHADAP 8000 PENGGUNA
Masalah Yang Diteliti Jumlah Pengguna Peratus Manfaat
Kanser              847   67
Masalah Jantung          1,058   80
Stroke              983   58
Diabetes tahap 1 dan 2         2,434   83
Kurang tenaga          7,931   91
Gangguan kenikmatan seksual        1,545   88
Kelemahan otot tubuh            709   71
Kegemukan (obesiti)          2,638   72
Tekanan darah tinggi            721   87
Berhenti merokok             447   58
Arthritis              673   80
Sakit kepala           3,785   87
Depresi               781   77
Alergi                851   85
Masalah Pencernaan          1,509   89
Masalah pernapasan          2,727   78
Gangguan tidur           1,148   72
Gangguan konsentrasi             301   89
Perasaan (senang/nyaman)          3,716   73
Masalah ginjal           2,127   66
Stress             3,273   71
* Sumber dari Noni Nature’s amazing healer, tulisan Neil Solomon.
Sumber :  http://www.akarkayu.com/?p=26